Whole-blood methylation signatures are associated with and accurately classify multiple sclerosis disease severity - Click here to find more information
Read moreSwitching to natalizumab or fingolimod in multiple sclerosis: Comparative effectiveness and effect of pre-switch disease activity - Click here to find more information
Read moreHeterogeneity on long-term disability trajectories in patients with secondary progressive MS: a latent class analysis from Big MS Data network - Click here to find more information
Read moreVariability of the response to immunotherapy among subgroups of patients with multiple sclerosis - Click here to find more information
Read moreThe MSBase Pregnancy, women’s health and neonatal outcomes sub-committee was formed in 2020 and seeks to build a comprehensive, international, prospective, observational pregnancy, neonatal outcomes and women’s health registry, integrated into the MSBase Registry to conduct safety, efficacy and clinical outcomes research. This key paper describes the productivity of the subcommittee and structure of the MSBase pregnancy registry effort. Well done to Vilija (Co-Chair and Scientific sub-committee Lead) and all members of the sub-committee!
The MSBase pregnancy, neonatal outcomes, and women’s health registry.
Research highlights contained within.
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Congratulations to Wei Yeh and the MSBase investigators for their recent publication in Neurology. Wei is a PhD student currently supervised by Dr Vilija Jokubaitis at the Central Clinical School of Monash University, Melbourne.
Research highlights contained within.
Read moreCongratulations to Helmut Butzkueven and the MSBase investigators for the recent publication in the European Journal of Neurology. This research was in collaboration with F. Hoffmann-La Roche Ltd.
Research highlights contained within.
Read moreCongratulations to Izanne and the MSBase Study Group for their recent publication. Izanne is part of the Clinical Outcomes Research (CORe) team in Melbourne, led by Prof Tomas Kalincik.
Determinants of therapeutic lag in multiple sclerosis.
Research highlights contained within.
Read moreCongratulations to Tomas Kalincik and the MSBase investigators for their recent publication in Neurology:
Research highlights contained within.
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Francesca Bovis was the recipient of an MSBase Fellowship award in 2018. Francesca is a post-doc Researcher in Biostatistics at the University of Genoa. The aim of her fellowship project was to utilise MSBase Registry data to apply an innovative statistical approach, developed at the Harvard Medical School, devoted to developing strategies that identify the patient population with the highest benefit from a drug.
Her findings related to this research have been published in Neurology:
Treatment response score to glatiramer acetate or interferon beta-1a.
Congratulations to Francesca Bovis, her fellowship supervisors Claudio Solaro and Maria Pia Sormani and all MSBase investigators who contributed to this achievement!
Read moreCongratulations to Izanne Roos and the MSBase investigators for their recent publication in Brain:
Delay from treatment start to full effect of immunotherapies for multiple sclerosis.
Research highlights contained within.
Read moreCongratulations to Vilija Jokubaitis and Ai-Lan Nguyen who led the first major comprehensive study confirming that pregnancy can slow MS onset. The study found that women who have been pregnant were diagnosed with their first MS symptoms, on average, 3.3 years later, compared to women who had never been pregnant.
Research findings have been published in the Journal of the American Medicine Association Neurology journal:
Association of Pregnancy With the Onset of Clinically Isolated Syndrome.
Congratulations to all MSBase collaborators involved in this very exciting and high impact publication!
Research highlights contained within.
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MSBase is pleased to announce a total of 10 accepted abstracts for presentation at MSVirtual - our first virtual ECTRIMS conference!
This is an excellent contribution from the MSBase collaboration. Congratulations to all investigators involved!
Lead authors and research details are contained within...
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Congratulations to Nathaniel Lizak and the MSBase investigators for their recent publication in JAMA Neurology!
Association of sustained immunotherapy with disability outcomes in patients with active secondary progressive multiple sclerosis.
Research highlights contained within.
Read moreCongratulations to Amy Kunchok and the MSBase investigators for their recent publication in Multiple Sclerosis Journal.
Prediction of on-treatment disability worsening in RRMS with the MAGNIMS score.
Research highlights contained within.
Read moreCongratulations to Minh Le and the MSBase investigators for their recent publication in Multiple Sclerosis Journal.
Disability outcomes of early cerebellar and brainstem symptoms in multiple sclerosis.
Research highlights contained within.
Read moreCongratulations to Nathanial Lizak, Suzanne Hodgkinson and the MSBase sub-study collaborators for their recent publication in Multiple Sclerosis Journal:
Real-world effectiveness of cladribine for Australian patients with multiple sclerosis: An MSBase registry substudy.
Research highlights contained within.
Read moreCongratulations to Charles Malpas and the MSBase investigators for their recent publication in Brain:
Early clinical markers of aggressive multiple sclerosis.
Research highlights contained within.
Read moreMSBase is pleased to advise that a COVID-19 specific data recording tool for both MDS and iMed is in development.
In the interim, there is a PDF version of the data recording form available via our Documents and resources page (or via this link)
Read more for details.
Read moreCongratulations to Anna He and the MSBase investigators for their recent Lancet Neurology publication:
Timing of high-efficacy therapy for multiple sclerosis: a retrospective observation cohort study
Research highlights contained within.
Read moreCongratulations to Amy Kunchok and MSBase collaborators for their latest research article published in Multiple Sclerosis and Related Disorders:
Clinical and therapeutic predictors of disease outcomes in AQP4-IgG+ neuromyelitis optica spectrum disorder
Read more for research highlights.
Read moreCongratulations to Adam Fambiatos, Vilija Jokubaitis and the MSBase collaborators for their recent publication in the Multiple Sclerosis journal:
Risk of secondary progressive multiple sclerosis: A longitudinal study
Research highlights contained within.
Read moreMSBase is pleased to announce a total of 14 accepted abstracts for presentation at ECTRIMS in Stockholm this year.
This is an excellent contribution from the MSBase collaboration. Congratulations to all involved!
Lead authors and research details are contained within...
Read moreCongratulations to Tomas Kalincik and Helmut Butzkueven for their recent review article highlighting the significant contribution of the MSBase Registry collaboration and its impact on Multiple Sclerosis management:
The MSBase registry: Informing clinical practice.
Read moreCongratulations to Will Brown, Tomas Kalincik and the MSBase investigators for their recent JAMA publication:
Association of Initial Disease-Modifying Therapy with later conversion to Secondary Progressive Multiple Sclerosis
Research highlights contained within.
Read moreCongratulations to Tomas Kalincik and MSBase investigators for their latest comparative study published in Neurology, Neurosurgery & Psychiatry:
Comparison of fingolimod, dimethyl fumarate and teriflunomide for multiple sclerosis
Read more for further details.
Read moreCongratulations to Ai-Lan Nguyen, Vilija Jokubaitis and MSBase collaborators for their latest research article published in Multiple Sclerosis and Related Disorders:
Incidence of pregnancy and disease-modifying therapy exposure trends in women with multiple sclerosis: A contemporary cohort study
Read more for research highlights.
Read moreCongratulations to Johannes Lorscheider and the MSBase investigators for their latest research article published in the European Journal of Neurology:
Anti-inflammatory disease modifying treatment and disability progression in primary progressive multiple sclerosis: a cohort study.
Further details contained within.
Read moreCongratulations to Myintzu Min, Jeannette Lechner-Scott and the MSBase collaborators for their research article published in the Multiple Sclerosis journal:
Read more for further details.
Read moreMSBase is happy to announce that nine abstracts will be presented at ECTRIMS in Berlin this year - a great contribution from the MSBase collaboration. Congratulations to you all!
Watch this space for the MSBase ECTRIMS presentations schedule.
Lead authors and research details contained within.
Read moreCongratulations to Ilya Kister on his latest MSBase collaborative research article published in the Journal of the Neurological Sciences:
Predictors of relapse and disability progression in MS patients who discontinue disease-modifying therapy.
Read more for research highlights and abstract.
Read moreCongratulations to Jordana Hughes, an MD research student working with Tomas Kalincik, on her recent publication in JAMA Neurology:
Association of Inflammation and Disability Accrual in Patients with Progressive-Onset Multiple Sclerosis.
Read more for further details.
Read moreTogether we have accumulated 60,000 patient records; an outstanding collaborative achievement by the members of the MSBase Registry.
This powerful pool of data can be used to address many important questions about MS, and will ultimately help to improve the lives of people living with MS.
Thank you for taking part and making a difference!
Read moreThe MSBase Fellowship Committee has selected Francesca Bovis from Italy as the successful MSBase Fellow for 2018. Francesca is a post-doc research fellow in Biostatistics at the University of Genoa. Her research focuses on statistical analysis of medical data with particular focus on methodological problems in the study of multiple sclerosis.
Read more for further details about the purpose and aims of Francesca's proposed research.
Read moreCongratulations to Yara Fragoso and the MSBase 'Lymphopenia and Efficacy of Fingolimod' sub-study Investigators on your research article:
Lymphocyte count in peripheral blood is not associated with the level of clinical response to treatment with fingolimod.
Read more below for details of the study.
Read moreThe Data Innovation Award is presented to an individual or team that that has developed the most innovative method of gathering, making available, processing or interpreting data in a way that advances health and medical research.
A huge congratulations to Helmut and the MSBase collaboration on receiving this prestigious award that recognises the growing success of MSBase to harness the power of real-world data, and ultimately help improve the lives of people with multiple sclerosis.
Read moreTomas Kalincik and the MSBase co-authors have delivered again with new research insights published in Brain:
Towards personalized therapy for multiple sclerosis: prediction of individual treatment response.
Congratulations Tomas and the MSBase Study Group.
Read moreMSBase is pleased to announce a total of 17 accepted abstracts for presentation at ECTRIMS in Paris this year. This is an excellent contribution from the MSBase collaboration. Congratulations to you all.
Watch this space for the MSBase ECTRIMS presentations schedule.
Lead authors and research details contained within.
Read moreCongratulations to Johannes Lorscheider, the MSBase co-authors and the MSBase study group on your recent peer-reviewed journal article published in Neurology:
Anti-inflammatory disease-modifying treatment and short-term disability progression in SPMS.
Read moreCongratulations to Tomas Kalincik, MSBase co-authors and the MSBase Study Group on a new publication in Multiple Sclerosis Journal.
Cladribine versus fingolimod, natalizumab and interferon β for multiple sclerosis.
Read moreCongratulations to Pietro Iaffaldano, the Italian iMedWeb Registry and the MSBase Registry:
Prognostic indicators in pediatric clinically isolated syndrome.
Read moreUnlocking the predictive power of routine clinical MRI - Click here to find more information
Read moreCongratulations to Alessio Signori, MSBase Fellowship recipient 2015!
Read moreDr Tomas Kalincik is advertising a postgraduate research scholarship that has the potential to inform clinical practice of multiple sclerosis management globally
Read more