MSBase

MSBase pregnancy registry efforts published in Therapeutic Advances in Neurological Disorders. Congratulations Vilija Jokubaitis and committee members!

The MSBase Pregnancy, women’s health and neonatal outcomes sub-committee was formed in 2020 and seeks to build a comprehensive, international, prospective, observational pregnancy, neonatal outcomes and women’s health registry, integrated into the MSBase Registry to conduct safety, efficacy and clinical outcomes research. This key paper describes the productivity of the subcommittee and structure of the MSBase pregnancy registry effort. Well done to Vilija (Co-Chair and Scientific sub-committee Lead) and all members of the sub-committee!

The MSBase pregnancy, neonatal outcomes, and women’s health registry.

Research highlights contained within.

MSBase research published in Neurology. Congratulations Wei Yeh and the MSBase Study Group!

Congratulations to Wei Yeh and the MSBase investigators for their recent publication in Neurology. Wei is a PhD student currently supervised by Dr Vilija Jokubaitis at the Central Clinical School of Monash University, Melbourne.

Natalizumab, fingolimod and dimethyl fumarate use and pregnancy-related relapse and disability in women with multiple sclerosis

Research highlights contained within.

MSBase research published in European Journal of Neurology. Congratulations Helmut Butzkueven and the MSBase Study Group!

Congratulations to Helmut Butzkueven and the MSBase investigators for the recent publication in the European Journal of Neurology. This research was in collaboration with F. Hoffmann-La Roche Ltd.

Risk of requiring a wheelchair in primary progressive multiple sclerosis: Data from the ORATORIO trial and the MSBase registry

Research highlights contained within.

MSBase research published in Multiple Sclerosis Journal. Congratulations Izanne Roos and the MSBase Study Group!

Congratulations to Izanne and the MSBase Study Group for their recent publication. Izanne is part of the Clinical Outcomes Research (CORe) team in Melbourne, led by Prof Tomas Kalincik.

Determinants of therapeutic lag in multiple sclerosis.

Research highlights contained within.

MSBase research published in Neurology. Congratulations Tomas Kalincik and the MSBase Study Group!

Congratulations to Tomas Kalincik and the MSBase investigators for their recent publication in Neurology:

Effect of disease modifying therapy on disability in relapsing remitting multiple sclerosis over 15 years. 

Research highlights contained within.

High impact MSBase paper published in Neurology by MSBase Fellow, Francesca Bovis!

Francesca Bovis was the recipient of an MSBase Fellowship award in 2018. Francesca is a post-doc Researcher in Biostatistics at the University of Genoa. The aim of her fellowship project was to utilise MSBase Registry data to apply an innovative statistical approach, developed at the Harvard Medical School, devoted to developing strategies that identify the patient population with the highest benefit from a drug.

Her findings related to this research have been published in Neurology:

Treatment response score to glatiramer acetate or interferon beta-1a.

Congratulations to Francesca Bovis, her fellowship supervisors Claudio Solaro and Maria Pia Sormani and all MSBase investigators who contributed to this achievement!

MSBase research published in Brain. Congratulations Izanne Roos and MSBase investigators!

Congratulations to Izanne Roos and the MSBase investigators for their recent publication in Brain:

Delay from treatment start to full effect of immunotherapies for multiple sclerosis.

Research highlights contained within.

World first pregnancy study findings published in JAMA! Congratulations Vilija Jokubaitis!

Congratulations to Vilija Jokubaitis and Ai-Lan Nguyen who led the first major comprehensive study confirming that pregnancy can slow MS onset. The study found that women who have been pregnant were diagnosed with their first MS symptoms, on average, 3.3 years later, compared to women who had never been pregnant. 

Research findings have been published in the Journal of the American Medicine Association Neurology journal:

Association of Pregnancy With the Onset of Clinically Isolated Syndrome.

Congratulations to all MSBase collaborators involved in this very exciting and high impact publication!

Research highlights contained within.

MSVirtual 2020 - MSBase Presentations

MSBase is pleased to announce a total of 10 accepted abstracts for presentation at MSVirtual - our first virtual ECTRIMS conference!

This is an excellent contribution from the MSBase collaboration. Congratulations to all investigators involved!

Lead authors and research details are contained within...

MSBase research published in JAMA Neurology. Congratulations Nathaniel Lizak and MSBase investigators!

Congratulations to Nathaniel Lizak and the MSBase investigators for their recent publication in JAMA Neurology!

Association of sustained immunotherapy with disability outcomes in patients with active secondary progressive multiple sclerosis.

Research highlights contained within.

MSBase research published in Multiple Sclerosis Journal. Congratulations Amy Kunchok and MSBase investigators!

Congratulations to Amy Kunchok and the MSBase investigators for their recent publication in Multiple Sclerosis Journal.

Prediction of on-treatment disability worsening in RRMS with the MAGNIMS score.

Research highlights contained within.

MSBase research published in Multiple Sclerosis Journal. Congratulations Minh Le and MSBase investigators!

Congratulations to Minh Le and the MSBase investigators for their recent publication in Multiple Sclerosis Journal.

Disability outcomes of early cerebellar and brainstem symptoms in multiple sclerosis.

Research highlights contained within.

MSBase Registry sub-study results published in Multiple Sclerosis Journal. Congratulations Nathanial Lizak, Suzanne Hodgkinson and MSBase collaborators!

Congratulations to Nathanial Lizak, Suzanne Hodgkinson and the MSBase sub-study collaborators for their recent publication in Multiple Sclerosis Journal:

Real-world effectiveness of cladribine for Australian patients with multiple sclerosis: An MSBase registry substudy.

Research highlights contained within.

MSBase research published in Brain! Congratulations Charles Malpas and MSBase investigators!

Congratulations to Charles Malpas and the MSBase investigators for their recent publication in Brain:

Early clinical markers of aggressive multiple sclerosis.

Research highlights contained within.

Update from MSBase on COVID data recording

MSBase is pleased to advise that a COVID-19 specific data recording tool for both MDS and iMed is in development.

In the interim, there is a PDF version of the data recording form available via our Documents and resources page (or via this link)

Read more for details.

MSBase research article published in Lancet Neurology: Congratulations Anna He & the MSBase investigators

Congratulations to Anna He and the MSBase investigators for their recent Lancet Neurology publication:

Timing of high-efficacy therapy for multiple sclerosis: a retrospective observation cohort study

Research highlights contained within.

MSBase research published in Multiple Sclerosis and Related Disorders journal: congratulations Amy Kunchok & the MSBase investigators

Congratulations to Amy Kunchok and MSBase collaborators for their latest research article published in Multiple Sclerosis and Related Disorders:

Clinical and therapeutic predictors of disease outcomes in AQP4-IgG+ neuromyelitis optica spectrum disorder

Read more for research highlights.

NEW MSBase research article published in Multiple Sclerosis journal

Congratulations to Adam Fambiatos, Vilija Jokubaitis and the MSBase collaborators for their recent publication in the Multiple Sclerosis journal:

Risk of secondary progressive multiple sclerosis: A longitudinal study

Research highlights contained within.

ECTRIMS 2019 - MSBase presentations

MSBase is pleased to announce a total of 14 accepted abstracts for presentation at ECTRIMS in Stockholm this year.

This is an excellent contribution from the MSBase collaboration. Congratulations to all involved!

Lead authors and research details are contained within...

An Informative review about MSBase recently published in Multiple Sclerosis Journal

Congratulations to Tomas Kalincik and Helmut Butzkueven for their recent review article highlighting the significant contribution of the MSBase Registry collaboration and its impact on Multiple Sclerosis management:

The MSBase registry: Informing clinical practice.

MSBase research published in JAMA: Congratulations Will Brown, Tomas Kalincik & the MSBase Investigators

Congratulations to Will Brown, Tomas Kalincik and the MSBase investigators for their recent JAMA publication:

Association of Initial Disease-Modifying Therapy with later conversion to Secondary Progressive Multiple Sclerosis

Research highlights contained within.

MSBase publication in Journal of Neurology, Neurosurgery & Psychiatry: congratulations Tomas Kalincik & the MSBase Investigators

Congratulations to Tomas Kalincik and MSBase investigators for their latest comparative study published in Neurology, Neurosurgery & Psychiatry:

Comparison of fingolimod, dimethyl fumarate and teriflunomide for multiple sclerosis  

Read more for further details.

MSBase research article published in Multiple Sclerosis and Related Disorders journal: congratulations Ai-Lan Nguyen, Vilija Jokubaitis & MSBase investigators

Congratulations to Ai-Lan Nguyen, Vilija Jokubaitis and MSBase collaborators for their latest research article published in Multiple Sclerosis and Related Disorders:

Incidence of pregnancy and disease-modifying therapy exposure trends in women with multiple sclerosis: A contemporary cohort study

Read more for research highlights.

MSBase publication in European Journal of Neurology: congratulations Johannes Lorscheider & the MSBase Investigators

Congratulations to Johannes Lorscheider and the MSBase investigators for their latest research article published in the European Journal of Neurology:

Anti-inflammatory disease modifying treatment and disability progression in primary progressive multiple sclerosis: a cohort study.

Further details contained within.

MSBase research article published in Multiple Sclerosis journal: congratulations Myintzu Min & Jeannette Lechner-Scott

Congratulations to Myintzu Min, Jeannette Lechner-Scott and the MSBase collaborators for their research article published in the Multiple Sclerosis journal:

Silent lesions on MRI imaging – Shifting goal posts for treatment decisions in multiple sclerosis

Read more for further details. 

MSBase investigators to present three oral and six poster presentations at ECTRIMS 2018

MSBase is happy to announce that nine abstracts will be presented at ECTRIMS in Berlin this year - a great contribution from the MSBase collaboration. Congratulations to you all!

Watch this space for the MSBase ECTRIMS presentations schedule.

Lead authors and research details contained within.

MSBase publication in Journal of the Neurological Sciences: congratulations Ilya Kister & the MSBase Investigators

Congratulations to Ilya Kister on his latest MSBase collaborative research article published in the Journal of the Neurological Sciences:

Predictors of relapse and disability progression in MS patients who discontinue disease-modifying therapy.

Read more for research highlights and abstract.

MSBase publication in JAMA Neurology: congratulations Jordana Hughes & MSBase Investigators

Congratulations to Jordana Hughes, an MD research student working with Tomas Kalincik, on her recent publication in JAMA Neurology:

Association of Inflammation and Disability Accrual in Patients with Progressive-Onset Multiple Sclerosis.

Read more for further details.

The MSBase Registry reaches 60,000 patient records!

Together we have accumulated 60,000 patient records; an outstanding collaborative achievement by the members of the MSBase Registry.

This powerful pool of data can be used to address many important questions about MS, and will ultimately help to improve the lives of people living with MS. 

Thank you for taking part and making a difference!

Fourth MSBase Research Fellowship awarded to Francesca Bovis

The MSBase Fellowship Committee has selected Francesca Bovis from Italy as the successful MSBase Fellow for 2018. Francesca is a post-doc research fellow in Biostatistics at the University of Genoa. Her research focuses on statistical analysis of medical data with particular focus on methodological problems in the study of multiple sclerosis.

Read more for further details about the purpose and aims of Francesca's proposed research.

MSBase research article published in Multiple Sclerosis and Related Disorders: congratulations Yara Fragoso and the MSBase Investigators!

Congratulations to Yara Fragoso and the MSBase 'Lymphopenia and Efficacy of Fingolimod' sub-study Investigators on your research article:

Lymphocyte count in peripheral blood is not associated with the level of clinical response to treatment with fingolimod.

Read more below for details of the study.

Prof Helmut Butzkueven receives Research Australia’s Data Innovation Award 2017 on behalf of the MSBase collaboration

The Data Innovation Award is presented to an individual or team that that has developed the most innovative method of gathering, making available, processing or interpreting data in a way that advances health and medical research.

A huge congratulations to Helmut and the MSBase collaboration on receiving this prestigious award that recognises the growing success of MSBase to harness the power of real-world data, and ultimately help improve the lives of people with multiple sclerosis.

New MSBase research article in Brain

Tomas Kalincik and the MSBase co-authors have delivered again with new research insights published in Brain:

Towards personalized therapy for multiple sclerosis: prediction of individual treatment response.

Congratulations Tomas and the MSBase Study Group.

MSBase oral and poster presentations for ECTRIMS 2017

MSBase is pleased to announce a total of 17 accepted abstracts for presentation at ECTRIMS in Paris this year. This is an excellent contribution from the MSBase collaboration. Congratulations to you all.

Watch this space for the MSBase ECTRIMS presentations schedule.

Lead authors and research details contained within.

New MSBase research article published in Neurology

Congratulations to Johannes Lorscheider, the MSBase co-authors and the MSBase study group on your recent peer-reviewed journal article published in Neurology:

Anti-inflammatory disease-modifying treatment and short-term disability progression in SPMS.

New MSBase article published in Multiple Sclerosis Journal

Congratulations to Tomas Kalincik, MSBase co-authors and the MSBase Study Group on a new publication in Multiple Sclerosis Journal.

Cladribine versus fingolimod, natalizumab and interferon β for multiple sclerosis.

New MSBase Publication in Annals of Neurology

Congratulations to Pietro Iaffaldano, the Italian iMedWeb Registry and the MSBase Registry:

Prognostic indicators in pediatric clinically isolated syndrome.

MSBase partners with Icometrix, Roche, Novartis and Biogen in world-first project

Unlocking the predictive power of routine clinical MRI - Click here to find more information

New MSBase Publication in Multiple Sclerosis Journal

Congratulations to Alessio Signori, MSBase Fellowship recipient 2015!

Postgraduate research scholarship opportunity Melbourne, Australia

Dr Tomas Kalincik is advertising a postgraduate research scholarship that has the potential to inform clinical practice of multiple sclerosis management globally